
Global SGLT2 Inhibitors Market Research Report: Forecast (2025-2030)
SGLT2 Inhibitors Market Size - By Drug Type (Jardiance [empagliflozin], Farxiga [dapagliflozin], Invokana [canagliflozin], Inpefa [sotagliflozin], Qtern [dapagliflozin/saxagliptin]..., Others), By Application (Type 2 Diabetes, Cardiovascular, Chronic Kidney Disease [CKD], Others), By End User (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies) and others Read more
- Healthcare
- Jul 2025
- Pages 190
- Report Format: PDF, Excel, PPT
Market Definition
SGLT2 Inhibitors are oral medications that are used to block the action of a protein found inside the kidneys called sodium-glucose co-transporter 2 (SGLT2), which is responsible for reabsorbing glucose from urine into the bloodstream, increasing blood-sugar levels.
Market Insights & Analysis: Global SGLT2 Inhibitors Market (2025-30):
The Global SGLT2 Inhibitors Market size was valued at around USD 18.41 billion in 2024 and is projected to reach USD 30.34 billion by 2030. Along with this, the market is estimated to grow at a CAGR of around 8.68% during the forecast period, i.e., 2025-30. The Global SGLT2 Inhibitor Industry is significantly growing due to several growth factors, including the rising burden of chronic disorders like type 2 diabetes, chronic kidney disorders, cardiovascular diseases, etc., the governmental support from different countries for the healthcare development & mass screening for these chronic disorders, the globally rising aging population, and the adoption of the next-generation SGLT2 inhibitors, and many more. One of the most prominent growth factors is the rapidly increasing elderly population globally, which is highly prone to these chronic disorders and highly demands early detection and better treatment solutions, thus increasing the demand for advanced medications such as SGLT2 inhibitors.
Report Coverage | Details |
---|---|
Historical Years | 2020–23 |
Base Years | 2024 |
Forecast Years | 2025–30 |
Market Value in 2024 | USD 18.41 Billion |
Market Value by 2030 | USD 30.34 Billion |
CAGR (2025–30) | 8.68% |
Leading Region | North America |
Top Key Players | Astellas, AstraZeneca, Boehringer Ingelheim International, Bristol-Myers Squibb Company, Eli Lilly and Company, Glenmark Pharmaceuticals, Johnson & Johnson (Janssen Pharmaceuticals), Lexicon Pharmaceuticals, Lupin Limited, Merck, Sanofi, TheracosBio, and Others |
Segmentation | By Drug Type (Jardiance [empagliflozin], Farxiga [dapagliflozin], Invokana [canagliflozin], Inpefa [sotagliflozin], Qtern [dapagliflozin/saxagliptin], Others), By Application (Type 2 Diabetes, Cardiovascular, Chronic Kidney Disease [CKD], Others), By End User (Hospital Pharmacies, Retail Pharmacies, Online Pharmacies) and others |
Key Report Highlights |
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Additionally, the governments form different countries, such as India, Indonesia, Canada, China, the US, etc., are actively supporting this market by heavily investing in the mass screening programs for different diseases, including type 2 diabetes. Also, the continuous research and development related to the SGLT2 inhibitor-based treatment for diseases other than type 2 diabetes are creating ample growth opportunities for this market to grow further. This leads to the rapid adoption of the advanced versions of the medicines, including the next-generation SGLT2 Inhibitors with enhanced efficiency and better treatment options over traditional ones.
However, the high upfront cost is a major challenge in this market, as it puts a financial barrier to a large number of the population, including the rural one. In addition, the lack of awareness among individuals, especially in rural and remote areas of the world, is further restraining the market’s growth & expansion.
Global SGLT2 Inhibitors Market Driver:
High Prevalence of Chronic Diseases – The market demand is driven by the high burden of chronic disorders globally, especially cardiovascular diseases, chronic disorders, and type 2 diabetes. For instance, as per the International Diabetes Federation (2021), there were over 540 million adult patients with type 2 diabetes globally, which is further expected to reach more than 640 million. Similarly, chronic kidney disease (CKD) is also highly prevalent globally, accounting for more than 840 million individuals all around the world. Also, more than 65 million individuals experience heart failure globally.
These are increasing the demand for advanced medication such as the SGLT2 Inhibitors, which can inhibit the action of the SGLT2 protein and are highly effective in overcoming these diseases, thus increasing market growth. It has led to the expansion of the SGLT2-inhibitor-based drugs' active pharmaceutical ingredient plants (API) worldwide. For instance, there are about 40-50 API plants globally that are specific to SGLT2 inhibitors.

Global SGLT2 Inhibitors Market Opportunity:
Mass Screening Program Through Government Support – The governments of different countries are actively supporting this market by introducing several initiatives and significant investments in the mass screening for chronic diseases, to upgrade the health status of their respective countries. For instance, Indonesia recently (in 2025) introduced a national screening initiative with an investment of around USD180 million to check the blood-sugar levels among 100 million individuals in the country. Also, the United Kingdom targets the audience for the screening of Chronic kidney diseases and diabetes in the country every five years.
Similarly, India offers health screenings for the early detection, management, and referrals for diabetes, cancer, and many other diseases, under the National Program for Prevention and Control of Non-Communicable Diseases (NP-NCD/NPCDCS), and has already screened millions of patients in both rural and urban areas of the country. Additionally, China offers free annual health screenings and testing for diabetes and CDK. These efforts are increasing the early detection and accelerating the demand for SGLT2 inhibitors’ prescription in countries with high prevalence and identification of diseases, thus contributing to the potential growth of this market.
Global SGLT2 Inhibitors Market Challenge:
High Cost & Limited Awareness Hindering Market Growth – The market is facing a high cost challenge that prevents a large portion of the individuals from accessing these medications completely, especially in the remote and rural areas of the underdeveloped and developing countries. For instance, a 30-day supply of the branded SGLT2 inhibitor medication can cost around USD600, while the traditional or generic forms are almost 90% cheaper than this. It is leading to a high preference for traditional medications globally, hence hindering the market growth & expansion.
Moreover, the limited awareness among healthcare providers and patients is further hindering the market growth. Many rural or underprivileged areas of the world lack appropriate health education, updated training, and delayed adoption, leading to unawareness of the SGLT2 inhibitors' roles in various other diseases like Chronic kidney disease and cardiovascular disorders. For instance, in the U.S. and Australia, less than 10% of the eligible patients are prescribed to take SGLT2 inhibitors. Similarly, only 18% of the diabetic patients were recommended to take SGLT2 inhibitor treatment, due to less awareness, thus restraining the market growth.
Global SGLT2 Inhibitors Market Trend:
Next-Generation SGLT2 Inhibitors Gaining Traction – The adoption of the next-generation SGLT2 inhibitors is positively transforming the market growth. The latest versions of these drugs are more effective, safer, and of high quality as compared to the traditional SGLT2 inhibitors. Several companies, such as Lexicon Pharmaceuticals, TheracosBio, Glenmark Pharmaceuticals, etc., have started actively manufacturing these second-generation drugs commercially, uplifting the market growth.
For instance, the company called TheracoBio has recently launched an affordable diabetes medicine, which was approved by the USFDA in 2023, and is considered to be the next-generation SGLT2 inhibitor because it contains more health benefits, like slight weight loss and reduced blood pressure. Similarly, Lexicon Pharmaceuticals has introduced a second-generation drug called Inpefa, which got FDA approval in 2023, is a dual inhibitor that can inhibit both SGLT1 and SGLT2 proteins to support other health problems, along with type 2 diabetes. These innovations are actively transforming market dynamics and paving the path for future growth & development.
Global SGLT2 Inhibitors Market (2025-30): Segmentation Analysis
The Global SGLT2 Inhibitors Market study of MarkNtel Advisors evaluates & highlights the major trends and influencing factors in each segment. It includes predictions for the period 2025–2030 at the global level. Based on the analysis, the market has been further classified as:
Based on Drug Type:
- Jardiance (empagliflozin)
- Farxiga (dapagliflozin)
- Invokana (canagliflozin)
- Inpefa (sotagliflozin)
- Qtern (dapagliflozin/saxagliptin)
- Others
Among these, the Jardiance (empagliflozin) holds the largest market share of about 32%. The dominance of this drug type is due to the high clinical performance over other kinds of drugs, proven by the large-scale clinical trials such as the EMPA-REG, DAPA-HF, and CREDENCE. For instance, the Eli Lilly company, with others, has conducted a study, including around 7,000 patients suffering from type 2 diabetes with a high risk of cardiovascular diseases. This study showed 38% fewer deaths from heart-related issues, 35% fewer hospital stays due to heart failure, and 32% lower risk of dying from any cause after using Jardiance. Similarly, all the other trials have shown the superiority and effectiveness of this drug as compared to other medicines, thus patients are preferring it more and increasing the revenue growth of the segment.
Additionally, this drug has been approved in more than 100 countries and is actively being produced globally, which is valued at around 2,000 tons per year. This widespread adoption is showing the dominance of this drug in the global market.
Based on End-User:
- Hospital Pharmacies
- Retail Pharmacies
- Online Pharmacies
Out of these, Hospital Pharmacies are dominating the Global SGLT2 Inhibitors Industry with a market share of more than 60%. The factor contributing to the market’s growth is the large volume of visits of serious diabetic patients to hospitals for regular check-ups, so they prefer to take medications, including SGLT2, recommended by the doctors, from the corresponding hospital pharmacies. Additionally, the beliefs related to the pharmacies in hospitals are also positively contributing to the growth & development of this segment.
Additionally, some of the medications, including SGLT2 inhibitors, are prescription drugs only worldwide, that is, only written in hospitals during the checkups, so it makes it easier for the patients to purchase the them from the nearest distribution channel, that is, the hospital pharmacies, thus leading the revenue growth of this segment in the SGLT2 Inhibitors Market.
Global SGLT2 Inhibitors Market (2025-30): Regional Projections
Geographically, the Global SGLT2 Inhibitors Market expands across:
- North America
- South America
- Europe
- The Middle East & Africa
- Asia-Pacific
North America holds the largest market share of more than 42%. The major reason behind its growth is the rising number of patients, especially the elderly population in the region, which is highly vulnerable to chronic diseases. For instance, as per the US Census (2024), over 58 million people are aged above 65 years, which represents about 18% of the total population of the country. Out of them, over 45 million senior citizens were diagnosed with chronic diseases in the United States.
Additionally, Canada accounts for more than 19% of the older population, and a substantial number of them are suffering from a chronic disorder. Also, 10% of the elderly population in Mexico has at least one chronic disease. This surge in the elderly population in North America is leading to a high demand for the latest medicines like SGLT2 inhibitors. These factors are contributing to the dominance of North America in the Global SGLT2 Inhibitors Market.
Global SGLT2 Inhibitors Industry Recent Development:
- 2024: Eli Lilly and Company launched a new combination therapy, bringing together its SGLT2 inhibitor Jardiance (empagliflozin) with a GLP-1 agonist. This new treatment helps improve blood sugar control and supports weight loss in people with type 2 diabetes, offering a more effective option for managing the condition.
Gain a Competitive Edge with Our Global SGLT2 Inhibitors Market Report
- Global SGLT2 Inhibitors Market Report by MarkNtel Advisors provides a detailed & thorough analysis of market size & share, growth rate, competitive landscape, and key players. This comprehensive analysis helps businesses gain a holistic understanding of the market dynamics & make informed decisions.
- This report also highlights current market trends & future projections, allowing businesses to identify emerging opportunities & potential challenges. By understanding market forecasts, companies can align their strategies & stay ahead of the competition.
- Global SGLT2 Inhibitors Market Report aids in assessing & mitigating risks associated with entering or operating in the market. By understanding market dynamics, regulatory frameworks, and potential challenges, businesses can develop strategies to minimize risks & optimize their operations.
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Frequently Asked Questions
- Market Segmentation
- Introduction
- Product Definition
- Research Process
- Assumptions
- Executive Summary
- Global SGLT2 Inhibitors Market Regulations, Policies & Product Standards
- Global SGLT2 Inhibitors Market Trends & Developments
- Global SGLT2 Inhibitors Market Dynamics
- Drivers
- Challenges
- Global SGLT2 Inhibitors Market Hotspots & Opportunities
- Global SGLT2 Inhibitors Market Value Chain Analysis
- Global SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type
- Jardiance (empagliflozin) - Market Size & Forecast 2020-2030, USD Million
- Farxiga (dapagliflozin) - Market Size & Forecast 2020-2030, USD Million
- Invokana (canagliflozin) - Market Size & Forecast 2020-2030, USD Million
- Inpefa (sotagliflozin) - Market Size & Forecast 2020-2030, USD Million
- Qtern (dapagliflozin/saxagliptin) - Market Size & Forecast 2020-2030, USD Million
- Others- Market Size & Forecast 2020-2030, USD Million
- By Application
- Type 2 Diabetes- Market Size & Forecast 2020-2030, USD Million
- Cardiovascular- Market Size & Forecast 2020-2030, USD Million
- Chronic Kidney Disease (CKD) - Market Size & Forecast 2020-2030, USD Million
- Others- Market Size & Forecast 2020-2030, USD Million
- By End User
- Hospital Pharmacies- Market Size & Forecast 2020-2030, USD Million
- Retail Pharmacies- Market Size & Forecast 2020-2030, USD Million
- Online Pharmacies- Market Size & Forecast 2020-2030, USD Million
- By Region
- North America
- South America
- Europe
- The Middle East & Africa
- Asia-Pacific
- By Company
- Revenue Shares
- Competition Characteristics
- By Drug Type
- Market Size & Analysis
- North America SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By Indication - Market Size & Forecast 2020-2030, USD Million
- By Frequency Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- By Country
- The US
- Canada
- Mexico
- The US SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- Market Size & Analysis
- Canada SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- Market Size & Analysis
- Mexico SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- Market Size & Analysis
- Market Size & Analysis
- South America SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By Indication - Market Size & Forecast 2020-2030, USD Million
- By Frequency Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- By Country
- Brazil
- Argentina
- Rest of South America
- Brazil SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
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- Argentina SGLT2 Inhibitors Market Outlook, 2020-2030F
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- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
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- Market Size & Analysis
- Europe SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By Indication - Market Size & Forecast 2020-2030, USD Million
- By Frequency Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- By Country
- Germany
- The UK
- France
- Spain
- Italy
- Rest of Europe
- Germany SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- Market Size & Analysis
- The UK SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
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- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
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- France SGLT2 Inhibitors Market Outlook, 2020-2030F
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- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
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- Spain SGLT2 Inhibitors Market Outlook, 2020-2030F
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- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
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- Italy SGLT2 Inhibitors Market Outlook, 2020-2030F
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- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
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- Market Size & Analysis
- The Middle East & Africa SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By Indication - Market Size & Forecast 2020-2030, USD Million
- By Frequency Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- By Country
- The UAE
- Saudi Arabia
- South Africa
- Rest of the Middle East & Africa
- The UAE SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
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- Market Size & Analysis
- Saudi Arabia SGLT2 Inhibitors Market Outlook, 2020-2030F
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- By Drug Type- Market Size & Forecast 2020-2030, USD Million
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- South Africa SGLT2 Inhibitors Market Outlook, 2020-2030F
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- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- Market Size & Analysis
- Market Size & Analysis
- Asia-Pacific SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By Indication - Market Size & Forecast 2020-2030, USD Million
- By Frequency Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- By Country
- China
- India
- Japan
- South Korea
- Australia
- Rest of Asia-Pacific
- China SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- Market Size & Analysis
- India SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- Market Size & Analysis
- Japan SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- Market Size & Analysis
- South Korea SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- Market Size & Analysis
- Australia SGLT2 Inhibitors Market Outlook, 2020-2030F
- Market Size & Analysis
- Market Revenues (USD Million)
- Market Share & Analysis
- By Drug Type- Market Size & Forecast 2020-2030, USD Million
- By End User- Market Size & Forecast 2020-2030, USD Million
- Market Size & Analysis
- Market Size & Analysis
- Global SGLT2 Inhibitors Market Key Strategic Imperatives for Growth & Success
- Competitive Outlook
- Company Profiles
- Astellas
- Business Description
- Product Portfolio
- Strategic Alliances or Partnerships
- Recent Developments
- Financial Details
- Others
- AstraZeneca
- Business Description
- Product Portfolio
- Strategic Alliances or Partnerships
- Recent Developments
- Financial Details
- Others
- Boehringer Ingelheim International
- Business Description
- Product Portfolio
- Strategic Alliances or Partnerships
- Recent Developments
- Financial Details
- Others
- Bristol-Myers Squibb Company
- Business Description
- Product Portfolio
- Strategic Alliances or Partnerships
- Recent Developments
- Financial Details
- Others
- Eli Lilly and Company
- Business Description
- Product Portfolio
- Strategic Alliances or Partnerships
- Recent Developments
- Financial Details
- Others
- Glenmark Pharmaceuticals
- Business Description
- Product Portfolio
- Strategic Alliances or Partnerships
- Recent Developments
- Financial Details
- Others
- Johnson & Johnson (Janssen Pharmaceuticals)
- Business Description
- Product Portfolio
- Strategic Alliances or Partnerships
- Recent Developments
- Financial Details
- Others
- Lexicon Pharmaceuticals
- Business Description
- Product Portfolio
- Strategic Alliances or Partnerships
- Recent Developments
- Financial Details
- Others
- Lupin Limited
- Business Description
- Product Portfolio
- Strategic Alliances or Partnerships
- Recent Developments
- Financial Details
- Others
- Merck
- Business Description
- Product Portfolio
- Strategic Alliances or Partnerships
- Recent Developments
- Financial Details
- Others
- Sanofi
- Business Description
- Product Portfolio
- Strategic Alliances or Partnerships
- Recent Developments
- Financial Details
- Others
- TheracosBio
- Business Description
- Product Portfolio
- Strategic Alliances or Partnerships
- Recent Developments
- Financial Details
- Others
- Others
- Astellas
- Company Profiles
- Disclaimer
MarkNtel Advisors follows a robust and iterative research methodology designed to ensure maximum accuracy and minimize deviation in market estimates and forecasts. Our approach combines both bottom-up and top-down techniques to effectively segment and quantify various aspects of the market. A consistent feature across all our research reports is data triangulation, which examines the market from three distinct perspectives to validate findings. Key components of our research process include:
1. Scope & Research Design At the outset, MarkNtel Advisors define the research objectives and formulate pertinent questions. This phase involves determining the type of research—qualitative or quantitative—and designing a methodology that outlines data collection methods, target demographics, and analytical tools. They also establish timelines and budgets to ensure the research aligns with client goals.
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4. Data Forecast and FinalizationThe final phase involves forecasting future market trends based on the analyzed data. MarkNtel Advisors utilize predictive modeling and time series analysis to anticipate market behaviors. The insights are then compiled into comprehensive reports, featuring visual aids like charts and graphs, and include strategic recommendations to inform client decision-making