Malignant melanoma is a tumor produced by the neoplasm (uncontrolled growth) of melanocytes derived from the neural crest. It usually occurs on the skin but can further spread in other areas where neural crest cells migrate. Most melanomas in the early stages do not present any particular symptoms. However, later they may appear as an already existing mole that displays size/color differences or lesions that do not heal. Its prevalence is rapidly growing worldwide, more commonly among Whites than Blacks & Asians. Being aggressive in nature, it can spread to numerous atypical locations through metastasis and hence has a poor prognosis.
The Global Malignant Melanoma Market is projected to grow at around 7% CAGR during the forecast period, i.e., 2022-27. The mounting patient pool for skin cancer & other skin allergies, rapidly increasing penetration of novel therapeutic agents, high unmet patient needs for melanoma treatment, and the launch of premium-priced therapies, like the combination of PD-1 and BRAF/MEK inhibitors, are the prime aspects driving the global market.
|Study Period||Historical Data: 2017-20|
|Base Year: 2021|
|Forecast Period: 2022-27|
|Regions Covered||North America: The US, Canada, Mexico|
|Europe: Germany, The UK, Germany, France, Italy, Spain, Rest of Europe|
|Asia-Pacific: China, Japan, India, Australia, South East Asia, Rest of Asia-Pacific|
|South America: Brazil, Rest of Latin America|
|Middle East & Africa: South Africa, GCC, Rest of Middle East & Africa|
|Key Companies Profiled||
AstraZeneca PLC, Amgen Inc., Bristol Myers Squibb, F. Hoffmann-La Roche AG, GlaxoSmithKline PLC, Merck & Co., Inc., Novartis International AG, Pfizer Inc., Sun Pharmaceutical Industries Ltd., Others
|Unit Denominations||USD Million/Billion|
Besides, various initiatives by governments of different countries worldwide for increasing the awareness about the early cancer detection & treatment, coupled with rapid technological advancements associated with the healthcare sector, and the advent of more effective diagnostics & therapeutics for malignant melanoma treatment, are also projected to boost the market in the coming years.
In general, the risk of developing malignant melanoma rises with age. However, new cases have been increasing among the younger population, i.e., those below 40 years. Moreover, there's a constantly surging need for affordable therapeutics for melanoma treatment owing to its burgeoning cost.
Surgery is the preferred method to treat primary skin cancer, but it alone fails for patients with advanced metastatic melanoma and thus, requires enhanced therapeutics. In recent years, with an improved understanding of cancer biology, various new therapeutic agents with promising potential have emerged as effective treatments for advanced melanoma and, in turn, project remunerative prospects for the Global Malignant Melanoma Market through 2027.
Based on Treatment:
Amongst all treatments, immunotherapy holds the largest share in the Global Malignant Melanoma Market, mainly due to its effectiveness & increasing approvals for novel immuno-oncology agents for melanoma treatment. The immune checkpoint inhibitor Yervoy (Ipilimumab), followed by Opdivo (Nivolumab) & Keytruda (Pembrolizumab), would continue dominating the overall market through 2027. It attributes to their
Keytruda (pembrolizumab) is likely to get approval as a first-line treatment for malignant melanoma across the major markets worldwide. However, Yervoy, despite strong competition, would remain the market leader over the forecast years.
On the other hand, targeted therapies have been gaining significant momentum in the field of oncology, including malignant melanoma, owing to their minimum adverse effects on patient health and enhanced efficiency. FDA-approved targeted agents for melanoma treatment include Mekinist (Trametinib) & Tafinlar (Dabrafenib), both alone and combined, as well as the combination of Zelboraf & Cobimetinib.
Based on Diagnosis:
Of all diagnoses, a biopsy remains the only foolproof method of determining if it is cancer, wherein a small sample of tissue gets tested in a laboratory. Other tests are also further prescribed to determine the overall stage of melanoma. Now it solely depends on the skin condition what type of biopsy would take place, and most often, the complete suspected area is cut using a scalpel.
Excision biopsy, wherein the entire tumor and a small margin of normal skin around it gets removed, is the recommended method for suspected malignant melanoma as it enables tumor diagnosis & staging while determining future investigation, treatment, & prognosis. On the other hand, incision biopsy is recommended only for large lesions, either on the face or acral areas.
In some cases, biopsies of areas other than the skin become necessary. For instance, a sentinel lymph node biopsy is the recommended diagnosis to know if cancer has spread to lymph nodes. If they have melanoma, i.e., a positive sentinel lymph node, it cites that cancer has spread, which calls for different treatments depending upon the situation.
Geographically, the Global Malignant Melanoma Market expands across:
Amongst all regions globally, North America dominated the Malignant Melanoma Market and is much likely to continue its dominance during 2022-27. The rising incidence of melanoma skin cancer, growing availability of cancer therapeutics, especially premium-priced drugs, and favorable policies for healthcare reimbursements to cater to the unmet needs of patients are the prime factors that would drive the regional market in the future.
North America is home to the leading biotechnology & pharmaceutical companies that are taking various strategic initiatives to boost their revenue shares. Moreover, patents on around 20 oncology biologics are approaching their expiration by 2023, which, in turn, would lead to more market entrants & biosimilar products in oncology & with reduced pricing. In addition, the well-established healthcare facilities, especially in the US & Canada, further project remunerative prospects for the Malignant Melanoma Market through 2027.
On the other hand, Asia-Pacific is likely to attain significant market growth through 2027, wherein India & China will be the fastest-growing markets for melanoma diagnostics & therapeutics. The regional market growth attributes primarily to the large population base and the constantly surging instances of malignant skin cancers.
Besides, rapid regulatory approvals for therapeutic drugs and the availability of cost-efficient therapies are also driving the market across Asia-Pacific. With the extensively available clinical research organizations in different countries of Asia-Pacific, several pharmaceutical & biotechnology firms are establishing themselves across the region to cater to the burgeoning demand for effective & affordable medications. Hence, these aspects would drive the Malignant Melanoma Market across Asia-Pacific over the forecast years.
Key Questions Answered in the Market Research Report:
Frequently Asked Questions
A. The Global Malignant Melanoma Market is projected to grow at a CAGR of around 7% during 2022-27.
A. The growing instances of skin cancer worldwide and numerous government initiatives for increasing the awareness regarding the early diagnosis & treatment are projected to drive the Global Malignant Melanoma Market during 2022-27.
A. The leading biotechnology & pharmaceutical companies worldwide conducting clinical trials of novel therapeutic agents for advanced melanoma treatment is the key trend in the Global Malignant Melanoma Market that, in the coming years, would generate lucrative prospects for these firms to yield greater revenues.
A. Targeted therapy would emerge as an area of remunerative opportunities for the leading companies operating in the Global Malignant Melanoma Market over the forecast years.
A. Asia-Pacific is expecting a significant growth rate of the Malignant Melanoma Market through 2027, mainly due to the growing prevalence of skin cancer and increasing approvals for clinical trials for therapeutic drugs for melanoma treatment.