CRISPR Gene Editing Market Research Report: Forecast (2022-27)

Market Definition

CRISPR (Clustered regularly interspaced short palindromic repeats) technology is a powerful & precise nucleic acid-targeting editing tool for the genome. It enables scientists & researchers to easily alter the DNA sequences & modify gene function. The CRISPR Gene Editing technology has the potential to correct genetic defects and treat & prevent chronic ailments. The technology has proven to be an efficient way to alter genomes compared to previous editing techniques such as Zinc Finger Nucleases (ZFNs) and Transcription Activator-like Effector Nucleases (TALENs).

Moreover, the rising prevalence of genetic disorders & growing research & development in biotechnology companies to yield better genomic results are the major factors contributing to the growth of the Global CRISPR Gene Editing Market, 2027.

Market Insights

The Global CRISPR Gene Editing Market is projected to grow at a CAGR of around 18.24% during the forecast period, 2022-27. The market is expected to witness significant growth, owing to the increase in demand for genome editing technologies for treating genetic & chronic disorders in humans. Other factors driving the growth are the rising population resulting in growing food requirements & non-gene editing applications, including diagnostics & antiviral, among others.

Moreover, the continuous investments & research conducted by pharmaceutical companies, education institutions, and governments across the biotechnology & biopharmaceutical industries are the major factors augmenting the growth of the Global CRISPR Gene Editing market. For instance:

• In 2021, Vertex Pharmaceuticals & CRISPR Therapeutics amended their collaboration agreement for developing, manufacturing, and commercializing CTX001, an investigational CRISPR/Cas-9 therapy for sickle cell disease (SCD) & beta-thalassemia.

Furthermore, over the past few years, CRISPR technology has observed tremendous advancements & enabled researchers to manipulate human, plant, and animal genomes in unprecedented ways. With the new emanating CRISPR-Cas systems, including spCas9-NG, base editing, xCas9, Cpf1, Cas13, and Cas14, scientists predict that this technology has the potential to revolutionize different industries such as agriculture, biomedicine, and bioenergy.

Additionally, scientists believe that there is still a lot to uncover about CRISPR technology in the future. CRISPR could be beneficial in several areas, including correcting genetic disorders that cause diseases like Hypertrophic cardiomyopathy (HCM), a heart condition that affects approximately 1 in 500 people worldwide, as per a study published in PLOS One. In 2017, researchers from Oregon Health and Science University showed impressive results from an experiment that employed CRISPR to delete one of the defective genes in numerous viable human embryos, exhibiting the possibility of using CRISPR technology to eradicate this heritable disease. In the future, CRISPR can eliminate the microbes that cause disease.

Besides, the substantial investments by biopharmaceuticals & biotechnology companies made in the fields of gene therapy, genome engineering, drug discovery, molecular research, and clinical research are promoting the development of industry-specific CRISPR gene-editing technology. For instance:

• In 2021, Mammoth Biosciences raised USD195 million with more than USD1 billion. With the help of these funds, the company would broaden its toolkit of next-generation CRISPR systems through in vivo gene-editing therapeutics & disease detection.
• Similarly, in 2018, Arbor Biotechnologies raised USD15.6 million in series A funding with a new CRISPR-associated enzyme, Cas13d.

Key Trend in the Market

• Rising Adoption of CRISPR-edited Agriculture

CRISPR gene technology has become the most utilized & versatile technology in functional genomics & crop breeding. Genome editing has the ability to create inheritable & predictable mutations in specific genomic sites to produce the desired results in crop production & cultivation.

Hence, this has gradually boosted the requirement for CRISPR gene technology for oil crops, food crops, feed crops, fiber crops, and ornamental crops to enhance the crop quality & market value of agricultural products. Further, various countries are adopting CRISPR gene editing technologies to modify crop production with different required characteristics. For instance:

• In 2022, China approved the gene-edited crops, which have revolutionized the researchers to develop a wide array of wheat varieties resistant to fungal diseases & various others.

Therefore, the CRISPR gene-edited technologies opened up several new horizons for researchers to develop multiple crop varieties that have increased yields, resilience against climate change, and a better response to fertilizers.

Impact of COVID-19 on the Global CRISPR Gene Editing Market

The COVID-19 pandemic prompted pharmaceutical & biotechnology companies to invest in the research & development of vaccine production. Thus, the rising demand for vaccines & potential antiviral candidates has brought CRISPR gene-editing technologies to the forefront.

Moreover, as compared to the conventional diagnostics & treatment methods, genome editing tools such as CRISPR-Cas 12/13-based SHERLOCK, CARVER, ribozymes, RNAi silencing, and aptamer therapies played a vital role during the research process in the COVID-19 outbreak. These advanced tools & treatment methods have proven to be shorter & easier diagnosis procedures for targeted virus detection & killing.