Bone grafts and substitutes are implantable materials used for replacing missing bones or repairing bone fractures. Their osteogenic, osteoinductive, & osteoconductive characteristics facilitate faster bone healing & formation and osseous restoration. They are used extensively in bone injuries and the ankle, foot, hip surgeries & fractures. The various types of bone grafts & substitutes include allografts, autografts, synthetic, or xenografts. The rising cases of orthopedic surgeries owing to sports injuries & road accidents have led to the surging utilization of these materials worldwide.
The Global Bone Grafts And Substitutes Market is projected to grow at a CAGR of around 5.6% during the forecast period, i.e., 2022-27. The growth of the market is driven primarily by the increasing prevalence of orthopedic trauma & osteoarthritis and various advancements in bone grafts & substitutes like the launch of biocompatible synthetic grafts to reduce adverse reactions after surgeries.
Bone & joint disorders adversely impact the musculoskeletal system, which comprises bones, tendons, soft tissues, ligaments, & muscles that function together to support the body's weight and help an individual move. As a result, the leading market players are investing substantially in developing new products with better bioactivity, biocompatibility, & suitable mechanical properties.
|Study Period||Historical Data: 2017-20|
|Base Year: 2021|
|Forecast Period: 2022-27|
|Regions Covered||North America: USA, Canada, Mexico|
|Europe: Germany, The UK, Germany, France, Spain, Italy and Others|
|Asia-Pacific: China, India, Japan, South Korea, Australia and Others|
|South America: Brazil, Rest of South America|
|Middle East & Africa: South Africa and Others|
|Key Companies Profiled||AlloSource, Baxter, Biobank, DePuy Synthes, Inc., Geistlich Pharma AG, Medtronic, NuVasive, Inc., OST Développement, Smith & Nephew, Inc., Stryker Corporation, TBF Tissue Engineering, Wright Medical Group N.V., Zimmer Biomet|
|Unit Denominations||USD Million/Billion|
Besides, the rapidly expanding geriatric population, growing inclination toward minimally invasive surgeries, and the mounting awareness among patients about the benefits of bone regeneration through biologics are further augmenting the growth of the bone grafts & substitutes market.
In addition, the extensive availability of advanced bone grafts & substitutes materials in different shapes & sizes, the surging number of patients with orthopedic & periodontal diseases, and massive R&D investments in enhancing the bioactivity of bone grafts and substitutes are other crucial aspects projected to drive the global market in the coming years.
Key Trend in the Global Bone Grafts & Substitutes Market
The leading players operating in the Global Bone Grafts And Substitutes Market are conducting numerous research & development activities, with massive expenditure on developing novel materials. It owes to the snowballing demand for efficient bone graft substitutes for elective orthopedic surgeries due to trauma & fractures. Similarly, the growing number of patients undergoing spine surgeries is also encouraging market leaders to enhance the efficiency of their product offerings, owing to the mounting requirements of orthopedic patients for improved treatment outcomes. Hence, these aspects project lucrative growth prospects for the global market through 2027.
Impact of Covid-19 on the Global Bone Grafts & Substitutes Market
The onset of the Covid-19 pandemic in 2020 had a moderate impact on the overall growth of the Global Bone Grafts And Substitutes Market. With the reallocation of healthcare resources toward handling the pandemic, all elective medical procedures, including orthopedic surgeries, got postponed. Hospitals & specialty clinics reported a drastic decline in patient visits, owing to the imposition of lockdown & movement restrictions by governments of different countries worldwide to curb the spread of the pandemic. As a result, the leading players in the global market witnessed significant revenue losses owing to disruptions in the supply chain activities and the unavailability of the workforce at production facilities for manufacturing bone grafts and substitutes.
However, despite substantial investments by governments in the treatment of Covid-19 patients & vaccine development, R&D activities associated with bone grafts and substitutes remained unhampered amidst the crisis, owing to which various innovative products got introduced. Furthermore, with the upliftment of lockdowns & stringent restrictions in several countries and the recommencement of elective surgeries & procedures across hospitals, the demand for bone grafts and substitutes, especially for dental applications, is witnessing a rapid rise, i.e., projecting lucrative growth prospects for the global market during 2022-27.
Based on Material Type:
Amongst all, synthetic materials are the major contributor to the growth of the Global Bone Grafts And Substitutes Market. It attributes mainly to their excellent biocompatibility, lesser risk of infections, and better acceptance rate among patients than allografts.
There are two types of synthetic materials, viz., polymer & ceramic. Here, ceramics are easily reabsorbed by the body & substituted by native bone tissue, which preserves the bone position & reduced the chances of disease transmission. Of both synthetic materials, ceramics hold the largest share of the global market, owing to limited blood loss & less pain involved, and the duration of surgery is short.
On the other hand, allograft & autograft materials also have a notable share in the global market owing to their characteristics like immediate structural support & osteoconductivity, along with rapid healing. The hip, knee, & spine are the areas where these materials are applied profoundly.
Based on Application:
Here, the Spinal Fusion application holds the majority market share, and the same trend is likely during 2022-27. It attributes primarily to the favorable characteristics of bone graft substitutes like bone graft extenders, particularly for posterolateral spinal fusion, coupled with the surging demand for bone graft materials for spondylosyndesis, and the growing geriatric population, i.e., prone to orthopedic ailments.
Spine fusion surgery has emerged as one of the most widely performed surgeries worldwide, owing to which the demand for autograft & allograft has observed consistent growth in recent years. Moreover, the rising prevalence of spinal disorders & various road accidents that happen worldwide is another crucial aspect projected to drive the global market for spinal fusion surgeries through 2027.
Based on End-Users:
Amongst both end-users, hospitals are more likely to dominate the global market during 2022-27. It attributes to the mounting reliance of patients on hospitals for spinal fusion & joint reconstruction surgeries, the extensive availability of numerous reconstructive techniques & synthetic bone grafts across these facilities, coupled with the quick & hassle-free insurance claim reimbursement.
On the other hand, specialty clinics, which offer safer & quicker procedures, are projected to register the highest growth rate through 2027, primarily due to the increasing inclination of patients toward specialist & focused orthopedic care across both the emerging & developing countries.
Geographically, the Global Bone Grafts And Substitutes Market expands across:
Of all regions globally, North America is the dominant region in the Bone Grafts And Substitutes Market, and the same trend is expected over the forecast years. The rapidly growing interest of patients in minimally invasive procedures, the well-established healthcare infrastructure, and the soaring utilization of allografts & other substitutes are the prime aspects driving the bone grafts & substitutes market across the region.
Moreover, the increasing number of orthopedic surgeries, the extensive presence of the leading market players, rising adoption of synthetic substitutes, massive expenditure on the medical sector, and various new product launches are other crucial aspects contributing to the dominance of North America in the market. The US leads the regional market, with the maximum demand for bone grafts and substitutes owing to the surging instances of trauma-related injuries & orthopedic diseases across the country, coupled with increasing technological advancements in the healthcare sector.
Key Questions Answered in the Market Research Report:
Frequently Asked Questions
A. The Global Bone Grafts And Substitutes Market is expecting around 5.6% CAGR during the forecast period i.e., 2022- 27.
A. The surging instances of orthopedic trauma worldwide and increasing R&D investments toward improving the bioactivity of bone grafts & substitutes are the key factors projected to drive the Global Bone Grafts & Substitutes Market through 2027.
A. Spinal Fusion is anticipated to emerge as an area of remunerative opportunities for the leading players in the Global Bone Grafts & Substitutes Market over the forecast years.